Radio-pharmaceuticals for cancer treatment: are they ready for prime time yet?
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Cancer Biomarkers: Are We Ready for the Prime Time?
A biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention. In cancer, a biomarker refers to a substance or process that is indicative of the presence of cancer in the body. A biomarker might be either a molecule secreted by a tumor or it can be a specific...
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Opening of the voltage-dependent Ca 2 channels permits influx of Ca across the plasma membrane, triggering diverse physiological processes. These channels are widely distributed in the cardiovascular system, constituting the main route for Ca entry essential for excitation and contraction. Ten unique 1 subunits, grouped in 3 families (CaV1, CaV2, and CaV3), that encode the low-voltage– activate...
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Metabolomics is one of the most rapidly growing areas of contemporary science. Although classic genetics aims to link variations in the DNA sequence directly to distinct phenotypes, “-omic” technologies allow us to shift the focus from the specific gene to the actual effects of the gene itself. Because neither the transcriptional or protein profile can be directly correlated with metabolite con...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2018
ISSN: 0923-7534
DOI: 10.1093/annonc/mdy142